4th International Caparica Conference in SPLICING 2021

26th – 29th July 2021 | Caparica | Portugal

Dear Colleagues and friends

It is estimated that 30% of diseases caused by mutations can be linked to splicing. Mutation of a splice site can result in site loss of function and specificity, causing insertion or deletion of aminoacids or a disruption of the reading frame. The importance of understanding and properly decoding roles governing splicing have become a fact for the research community as demonstarted by the increasing number of manuscripts devoted to this subject. Splicing 2021 intends to join in a friendly academic environment all of us working or interested in moving to this area of research. The conference will take place in summer in one of the best beach areas from Portugal, the sea village of Caparica (South Lisbon area). We aim you to present your latest results in Splicing and to join the best researchers in this area of knowledge. Please do not hesitate in contacting me should you have any suggestion to help us make of this event a remarkable one.


Yours truly

C. Lodeiro

 J. L. Capelo
Conference chairs
On behalf of the organizing and scientific committee

Plenary Speakers

Lorna Harries, PhD

Affiliation: University of Exeter Medical School, Exeter (UK)

Title: A tale of three FOXes – Forkhead genes at the interface between RNA biology and longevity.

Benoit Chabot, PhD

Affiliation: Département de microbiologie et d’infectiologie, Faculté de médecine et des sciences de la santé, Université de Sherbrooke (Canada)

Title: Splicing modulators to control cancer and senescence.

Steve Wilton, PhD

Affiliation: Murdoch University (Australia)

Title: Antisense oligomer induced spliceoform switching: from Duchenne muscular dystrophy to common serious inherited and acquired diseases.

Ruth Sperling, PhD

Affiliation: Department of Genetics, The Hebrew University of Jerusalem, Jerusalem (Israel)

Title: The endogenous spliceosome – a multi-task machine.

Yi Xing, PhD

Affiliation: Center for Computational and Genomic Medicine The Children’s Hospital of Philadelphia (USA)

Title: Alternative splicing in cancer transcriptomes.

Raymond Kaempfer, PhD

Affiliation: Biochemistry and Molecular Biology, Faculty of Medicine, The Hebrew University (Israel)

Title: HIV-1 co-opts a cellular antiviral mechanism, activation of PKR by its RNA, to control mRNA splicing.

Frans Cremers, PhD

Affiliation: Department of Human Genetics, Radboud University Medical Center, Nijmegen (The Netherlands)

Title: Stargardt disease-associated deep-intronic variants in ABCA4 result in complex splicing defects.



KPRK Talks

John Rasko, PhD

Affiliation: Head of Department, Cell & Molecular Therapies, Royal Prince Alfred Hospital, Sydney (Australia)

Title: Changing paradigms of intron retention.

Chonghui Cheng, PhD

Affiliation: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston (USA)

Title: Alternative RNA splicing contributes to cancer cell plasticity.

Keynote Speakers

Matthias Soller, PhD

Affiliation: School of Biosciences, College of Life and Environmental Sciences, University of Birmingham (UK)

Title: Alternative splicing regulation by m6A mRNA methylation in Drosophila sex determination.

Diana Baralle, PhD

Affiliation: University of Southampton, Southampton (UK)

Title: RNA and splicing in Genomic Medicine.

Ihab Younis, PhD

Affiliation: Carnegie Mellon University Qatar (Qatar)

Title: Targeting Deregulated Splicing in Breast Cancer.

Hui Li, PhD

Affiliation: School of Medicine, University of Virginia (USA)

Alexander Hüttenhofer, PhD

Affiliation: Innsbruck Medical University – Biocenter, Innsbruck (Austria)

Title: Intronic tRNAs of mitochondrial origin act as regulators of constitutive and alternative splicing.

David Bates, PhD

Affiliation: Division of Cancer and Stem Cells,School of Medicine,University of Nottingham (UK)

Lucy Donaldson, PhD

Affiliation: University of Nottingham, School of Life Sciences, Nottingham (UK)

Anthony Schweitzer, PhD

Affiliation: Thermo Fisher Scientific, Santa Clara (USA)

Michele Mishto, PhD

Affiliation: Centre for Inflammation Biology and Cancer Immunology (CIBCI) & Peter Gorer Department of Immunobiology, King’s College London, London (UK)

Title: 2004-2021: what we know about post-translational peptide splicing.

Beatrice Eymin, PhD

Affiliation: Institute For Advanced Biosciences, INSERM U1209/CNRS UMR5309/University Grenoble Alpes, Grenoble (France)

Title: Splice variants of the RTK family: their role in tumor progression and response to therapies.

Stephen Yi, PhD

Affiliation: University of Texas at Austin (USA)



Symposium Subjects

  • RNA Splicing
  • Protein Splicing
  • DNA Splicing
  • Alternative Splicing
  • Splicing and Disease
  • Splicing and Nanotechnology
  • Autosplicing
  • Espliceosome
  • Computacional Biology of Splicing
  • Translational Applications

Hotel Aldeia dos Capuchos

Be aware of cold calls from Convention Hotel Services (CHS) or from someone named Adam Max! A company called CHS (Convention Hotel Services) is calling or e-mailing attendees of conferences worldwide, claiming to work for the conference organizers and asking for credit card details to finalize the booking of accommodation. If you receive such a call or e-mail, do not give away any personal information or credit card details! None of the parties involved in the organization of SPLICING 2021 is working with CHS

We have received some alerts from participants this week regarding this email: Ehotel Services via DocuSign .

If you receive such a call or e-mail, do not give away any personal information or credit card details! This problem affects many conferences, not only the PROTEOMASS BIOSCOPE conferences.

We look forward to seeing you soon.

With kindest regards